By Dr Marek Zarzycki, Process Development Scientist Global production of therapeutic recombinant antibodies is worth over 100 billion US dollars. These antibodies can be used to treat a wide variety …
Development of scaleable production of empty CPMV Virus-like Particles. The advantages of virus-like particles (VLPs)
Case Study Viruses are comprised of several structural proteins which make up the outer shell of the virus particle. Genetic material (either RNA or DNA) is contained within the core …
Use of Agrobacterium in Plant Based Expression
Plant pathogens, such as Agrobacterium tumefaciens can transfer a segment of its DNA into the plant cell, resulting in the expression of the introduced genes. Development of these processes started …
10 to 10000 – Scaleability in Plant Production
Recombinant protein production by transient gene expression in plants provides an adaptable, robust and cost-effective alternative to some of the more traditional and established methods such as cell-based microbial and …
Novel Expression Systems for Production of Monoclonal Antibodies
Monoclonal Antibodies – challenges with current production techniques Monoclonal antibodies are increasingly used in a wide spectrum of therapeutic and diagnostic applications and global production levels are growing by 10% …
Innovation in Vaccination
According to the World Health Organisation’s paper on Global Vector Control, vector-borne diseases are a major health threat accounting for 17% of communicable diseases worldwide. They have a major …
Blue Tongue Virus (BTV)
Bluetongue disease is a non-contagious, insect-borne, viral disease of ruminants, mainly sheep and less frequently cattle, goats, buffalo, deer, dromedaries and antelope. First identified in South Africa, the virus has …
Virus-Free Polio Vaccine
The fight against polio has been one of the great success stories of modern medicine, with the disease already eliminated in much of the world. However, current immunisation programmes use …
Diagnostic for Zika virus
Although the Zika virus was first isolated in 1947 in the Zika Forest of Uganda, it was not until the emergence in Brazil in 2015 of this previously obscure tropical …