Leaf Expression Systems Launch First Line of Hypertrans® Research Products


Plant-expression deal for difficult to produce proteins, vaccines, metabolites and natural proteins


CPMV Cowpea Mosaic Virus (VLPs) Leaf Expression Systems

29 May 2019: Norwich, UK Leaf Expression Systems, a contract development and manufacturing organisation specialising in the plant-based expression and production of proteins, vaccines, metabolites and complex natural proteins, has announced the launch of its online list of products available for purchase by researchers working within the life sciences and agricultural industries.

The products are produced in Nicotiana benthamiana using Hypertrans®, Leaf’s Agrobacterium-mediated transient expression technology. Hypertrans® is efficient, safe and simple to use to quickly produce proteins, vaccines, antibodies or enzymes in plants.

The products; Bet v 1-A – Betula verrucosa (European white birch) allergen 1-A, Cowpea Mosaic Virus VLPs, Horseradish Peroxidase (HRP) C1A, Human Nucleotide triphosphate diphosphatase NUDT15 (MTH2), MAb Anti-VEGF 165A, Phleum pratense (Common timothy) allergen 1 and Triosephosphate Isomerase (TPI) are all available for purchase for research purposes via its online platform.

Simon Saxby, CEO said ‘We are excited to launch our first proprietary products produced in plants using Hypertrans®. We will continue to add products that are difficult or uneconomical to produce using other expression systems to add to the research tools available to the life science community and which also demonstrate the extreme flexibility and capability of Hypertrans® for the rapid manufacture of a wide range of biologics on commercially viable scales’.




Richard Hayhurst Associates
Richard Hayhurst

Leaf Expression Systems
Polly Ferris
Marketing and Communications Officer
Leaf Expression Systems
01603 859298


About Leaf Expression Systems

Leaf Expression Systems is a contract development and manufacturing business specialising in plant-based expression and production of proteins, vaccines and complex natural products for research and commercial applications.  It uses Hypertrans®, the proprietary transient expression technology.

The Hypertrans® system allows for the rapid simultaneous production of multiple gene products in a controlled and coordinated manner within the tissues of plants.  Using gene synthesis and modular vectors, new products such as vaccines, antibodies or enzymes can be produced at speed and on a large scale, so it is well suited to be able to rapidly respond to emergencies like pandemics.

Leaf Expression Systems is based in a purpose-built, state-of-the-art facility on Norwich Research Park, that boasts of four environmentally controlled growing rooms, plant potting areas, a plant inoculation area, microbiology/molecular biology labs, protein purification and natural product processing facilities.